It is common for acne to get worse when we pick or handle them often and after sleep at night. Picking and squeezing blackheads or acne makes them bleed and get infected with the bacteria on the face. Acne skin care products used to disinfect the area often with being patient helps. Next a natural spike in hormone levels could lead to acne becoming worse. The reasons could be polycystic ovary syndrome (POS), contraceptive pills and pregnancy, with men also experiencing it equally as women.
It is beneficial to note that certain medications used in epilepsy, steroid cream, and eczema ointments aggravate acne conditions. Your general practitioner/dermatologist would be the best person to advice you on use of medications and skin-care products.